Former two-time UFC middleweight champion Israel Adesanya will fight down in the rankings and try to snap a three-fight losing skid when he takes on Joe Pyfer in the UFC Fight Night 271 main event.

Israel Adesanya vs. Joe Pyfer preview

Adesanya (24-5 MMA, 13-5 UFC) is on a three-fight skid, most recently suffering a TKO loss to Nassourdine Imavov at UFC Fight Night 250 last February. He hasn’t won a fight since knocking out Alex Pereira to reclaim his middleweight title at UFC 287 in April 2023.

Pyfer (15-3 MMA, 6-1 UFC) rebounded from his first UFC loss to Jack Hermansson with three wins in a row, two of them by finish. He is coming off a Performance of the Night submission of Abus Magomedov at UFC 320 this past October.

Israel Adesanya vs. Joe Pyfer odds

According to DraftKings, Adesanya is a +110 underdog against Pyfer, who is currently a -130 betting favorite.

How to watch Israel Adesanya vs. Joe Pyfer

• Where: Climate Pledge Arena, Seattle, Washington
• Broadcast/streaming: Paramount+
• When: Saturday, March 28, 2026

This article originally appeared on MMA Junkie: Israel Adesanya vs. Joe Pyfer: Odds and what to know for UFC Seattle