The East leading Detroit Pistons will be without two key starters for at least the next week.

Center Jalen Duren, who is playing at an All-Star level this season, has suffered a right ankle sprain and will be re-evaluated in one week, the team announced. Duren has taken a big step forward this season, averaging 17.9 points per game on 63.3% shooting and 10.6 rebounds a game.

His absence means to expect more Isaiah Steward and Paul Reed at the five, which is about as good a backup center combo as there is in the league.

Wing Tobias Harris has a left hip sprain that will sideline him and have him re-evaluated in two weeks. Harris is averaging 13.4 points a game and is shooting 33.3% from 3-point range. Sixth man Caris LeVert is day-to-day with right knee inflammation and is not traveling with the team for its game this weekend in Cleveland.

It's a tough week for the Pistons to be without these starters as they face a Cavaliers team that has won three in a row, then the Knicks.